Traumatic Brain Injuries

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What is a traumatic brain injury?

Traumatic brain injuries (TBI) refer to sudden injuries that cause brain damage. Such injury may arise following a blow or bump to the head. It can be grouped into 2 main types:

• Penetrating (open head injury)
• Non-penetrating (close head injury)

The severity of a TBI may vary from mild, moderate, to severe depending on the initial impact and subsequent brain damage. Depending on the severity, someone may recover within a few days. But in more severe cases, a TBI could lead to more serious symptoms and consequences like coma, and even death.

What are the symptoms of a traumatic brain injury?

The symptoms of a TBI also varies depending on the severity and cause of the injury. Symptoms of the injury might occur directly after a blow or at the time of impact but also may appear much later for very trivial cases.

At times, people especially the elderly, don’t feel the effects of the injury for a few days after the blow. Common signs include:

  • Behaviour and mood changes, irritability
  • Fainting, loss of consciousness
  • Confusion and disorientation
  • Memory problems, memory loss, amnesia
  • persistent Headaches
  • Early morning nausea and vomiting
  • Dizziness and loss of balance
  • Sensitive to bright light
  • Tremors, poor coordination
  • First onset of Seizures
  • Loss of smell
  • Dilated pupils or blurred/double vision
  • Slurred speech, difficulty speaking, reading, or writing
  • Sleep disturbances
  • Feelings of depression and mood changes
  • Cerebrospinal fluid (CSF) leaking from ears or nose


In children and infants, some other signs include:

  • Inconsolable, nonstop crying
  • Refusing to eat or drink
  • Drowsiness
  • Loss of interest in favourite activities

When should you see a doctor?

If you have experienced a blow to the head, especially accompanied by the symptoms mentioned above, it is always a good idea to visit a doctor. Even mild or moderate injuries may require medical attention and appropriate investigations so it is always best to see a doctor and get an accurate diagnosis.

How are traumatic brain injuries caused?

As previously mentioned, a traumatic brain injury is classified into 2 main types:

Non-penetrating/ closed head injury may be caused by:

  • Falls
  • Car crashes and/or other vehicle-related accidents
  • Sports injuries
  • Struck by an object
  • Child abuse
  • Blast injuries due to explosions


Penetrating injury
may be caused by:

  • Being hit by a weapon/ firearms
  • A head injury that causes a bone fragment to penetrate the skull
  • Severe industrial accidents


In cases of natural disasters such as an earthquake and other extreme events, it is also possible for someone to experience both penetrating and non-penetrating brain injury at the same time.

What complications can arise from an untreated brain injury?

If left untreated, a traumatic brain injury can cause long-term and even permanent damage and disabilities. A traumatic brain injury also increases the risk of developing:

  • Anxiety, depression and post-traumatic stress disorder (PTSD)
  • Bleeding inside brain and weakness of arm and leg
  • Seizures (traumatic epilepsy)


Other complications include:

  • Cerebrospinal Fluid (CSF) build-up in the brain (hydrocephalus), which increases pressure and causes swelling in the brain
  • Infections including meningitis, which may spread to the rest of the nervous system
  • Blood vessel damage, which could lead to stroke and blood clots
  • Frequent headaches
  • Vertigo
  • Cranial nerve damage, which may lead to:
    • Paralysis of facial muscles
    • Swallowing problems
    • Loss of sense of smell or taste
    • Loss of vision
    • Hearing loss
    • Dizziness
  • Cognitive/ intellectual problems:
    • Memory loss
    • Impairment in learning, reasoning, judgement, and problem solving
    • Impaired attention or concentration
    • Mood disorders
  • Communication problems:
    • Difficulty speaking or writing
    • Difficulty understanding information
    • Inability to organise thoughts and ideas


While unlikely for mild to moderate traumatic brain injuries, severe cases can also increase the risks of developing early onset of Alzheimer’s disease, dementia, or movement disorders later in life.

What can I expect during my first consultation?

When someone with a traumatic brain injury comes to the emergency room, a doctor will assess the patient’s condition, symptoms, and cause of injury.

To test a patient’s level of consciousness, I generally use the Glasgow Coma Score (GCS). This test assesses the patient’s ability to:

  • Open their eyes
  • Ability to respond appropriately to orientation questions
  • Ability to follow commands
  • Respond to pain stimulation (if the person is unconscious or unable to follow commands)


The total score from each category is added together to get the final GCS score:

  • Mild TBI: 13 – 15
  • Moderate TBI: 9 – 12
  • Severe TBI: 8 and below

How are traumatic brain injuries diagnosed?

Following that, other diagnostic imaging tests will be done. These may include:

Computed Tomography (CT)

The first line of investigation in the diagnosis of head injury, a CT scan is a non-invasive imaging test that helps identify skull and skull base fractures, bleeding in the brain, blood clots, and the overall extent of brain injury and underlying brain swelling. CT scans will be taken a few times throughout the recovery process to observe the progression of the injury and treatment.

Magnetic Resonance Imaging (MRI)

A non-invasive test that utilises a magnetic field to visualise the soft tissues of the brain. The test may show subtle changes that are not seen in a CT scan, but as the test takes longer than a CT scan, it is usually only done after the patient has stabilised. It can give more detailed information about the brain after the injury and treatment.

Magnetic Resonance Spectroscopy (MRS)

A test to find information about the metabolism of the brain. Results of the MRS scan gives to exclude some complications and consequences related to the injury.

Cerebrospinal Fluid (CSF) Analysis

Above that, a cerebrospinal fluid (CSF) analysis may also be done. The CSF is collected through a procedure called a spinal tap. This involves inserting a thin, hollow needle between two vertebrae in the lower spine. The CSF analysis in traumatic brain injury is done to diagnose:

  • Infections, including meningitis and encephalitis
  • To measure the CSF pressures

How are traumatic brain injuries treated?

The treatment for a TBI will depend on the severity of the condition. For mild cases, the treatment may include symptomatic medications and subsequent clinical assessment with physiotherapy. Surgery is necessary for those with severe head injuries and bleeding or swelling inside the brain.

Medications

This treatment works to limit secondary damage immediately after the injury. This may include:

Anti-seizure drugs

A TBI increases the risk of seizures which may cause additional brain damage. The use of this drug may be continued if seizures continue to happen.

Coma-inducing drugs

The drug is used to put people to sleep, which is called temporary coma that will help the injured or swollen brain requires less oxygen to function and temporary rest.

Diuretics

To reduce the amount of fluid in tissues, thus reducing the pressure inside the brain.


Surgery

In some cases, emergency surgery may be necessary to minimise additional damage to the brain. The surgery may be done to:

• Remove blood clots
• Repair skull fractures
• Stop bleeding in the brain
• Relieve pressure inside the skull (by draining CSF or creating a window in the skull)

Treatment of severe traumatic brain injury

Referred to as neurocritical care, the intensive care of patients with severe TBI may include:

Monitoring

• Intracranial pressure (ICP) monitor
• Brain oxygen monitor (Licox)
• Ventilator
• Feeding tube
• Seizures and EEG monitoring

Medication

• Sedation and pain
• Controlling brain pressure (hypertonic saline)
• Preventing seizures (levetiracetam or phenytoin)
• Preventing infection

Treatment of severe traumatic brain injury

Surgery

This involves cutting a hole in the skull to remove a bone flap. The surgeon can then access the brain through the bone flap to remove the blood clot and repair the damaged brain membrane to prevent brain fluid leak.

Decompressive craniectomy

Performed when the pressure inside the brain increases to a life-threatening level, the surgery involves removing a large section of bone to allow the brain to swell and expand. The removed bone flap will be stored in a freezer and 1 – 3 months after the swelling has resolved, the bone flap will be replaced (called cranioplasty).

Evacuation of a cerebral blood clot (Burr hole drainage)

Either a small hole (burr hole) or craniotomy (larger bone opening) is created through the skull to suction out the blood clot, stop the bleeding areas and relieve brain pressure.

CSF leak repair

Using a synthetic graft, a piece of the patient’s own tissue, or using a flap of tissue to repair affected damage or tear areas in the skull base to prevent CSF leak.

Summary

The diagnosis, treatment, and management of traumatic brain injuries differ greatly depending on the severity and cause of injury. While some cases might be mild and come with few symptoms, other cases might be much more severe and even light threatening.

If you experienced a blow to the head or any of the symptoms mentioned above, it is always a good measure to visit a doctor. An accurate diagnosis is the start to effective treatment and recovery.

Dr Sein Lwin Author

Dr Sein Lwin

Senior Consultant Neuro & Spine Surgeon
MBBS, MSc Surgery, MRCS (Edin), MMed. Sc (Gen Surg) (S'pore), FRCS. Surgical Neurology (UK)

Dr Sein Lwin is an experienced Senior Consultant Neuro & Spine Surgeon and the Neurosurgical Director at the Advanced Brain and Spine Surgical Centre.

He is highly experienced in spine surgery and in minimally invasive approaches for spinal cord tumours and degenerative spine surgery. His specialised interests lie in endoscopic endonasal and open skull base surgery, pituitary tumours, vascular surgery, cranial nerve disorders and peripheral nerve conditions.

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